Preheat your oven to 375°F (190°C) and line a baking sheet with parchment paper.
In a skillet over medium heat, cook the ground beef until no longer pink, breaking it into small crumbles with a spatula. Drain any excess fat.
Season the beef with salt, black pepper, garlic powder, onion powder, and Worcestershire sauce. Stir in the shredded cheddar cheese until melted and well combined. Set aside to cool slightly.
On a lightly floured surface, roll out each biscuit to about 1/4 inch thick. Place about 2 tablespoons of the beef mixture in the center of each biscuit round.
Pull the edges of the dough up and over the filling, pinching firmly to seal. Place each ball seam-side down on the prepared baking sheet.
In a small bowl, whisk together the melted butter and minced garlic. Brush generously over the tops of each bomb.
Sprinkle grated Parmesan cheese evenly over the tops.
Bake for 12-15 minutes, or until golden brown and cooked through.
Remove from the oven and garnish with chopped fresh parsley. Serve warm.